Metoprolol tartrate, also known by the brand name Lopressor, is an immediate-release oral tablet that comes in strengths of 25 mg, 37.5 mg, 50 mg, 75 mg, and 100 mg. Metoprolol comes in two different salt forms: metoprolol tartrate and metoprolol succinate. Selective beta-blockers may have slightly different effects compared to non-selective beta-blockers. However, it also blocks beta-2 receptors, although to a lesser degree. Metoprolol is a beta-1 selective blocker that primarily blocks the beta-1 receptors in the heart. Carvedilol is also available in an extended-release form (Coreg CR) that can be taken once daily. It is usually taken as a 3.125 mg, 6.25 mg, 12.5 mg, or 25 mg oral tablet twice daily. Carvedilol also blocks alpha receptors in the arteries, which helps lower blood pressure.Ĭarvedilol is the generic name for Coreg. Beta-1 receptors are found in the heart while beta-2 receptors are primarily found in the smooth muscles. This means that carvedilol can block both beta-1 receptors and beta-2 receptors. What are the main differences between carvedilol and metoprolol?Ĭarvedilol is considered a non-selective beta-blocker. Although they share similarities, they also have differences in dosage, formulation, and side effects. Carvedilol and metoprolol are both generic medications.
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